drugset / Trial / NCT04241731

A Study of Cetuximab Plus Raltitrexed for Maintenance Treatment in Advanced Colorectal Cancer

NCT04241731

Phase 2 Unknown 50 enrolled Jiangsu Cancer Institute & Hospital
NaSingle-groupOpen-labelTreatment

Summary

Maintenance treatment can extend patient survival and improve patient quality of life. Bevacizumab alone or capecitabine combined with bevacizumab as a maintenance treatment have been widely used in clinical practice. In contrast, there are little datas of cetuximab as a maintenance treatment. The purpose of this study is to evaluate efficacy and safety of Raltitrexed plus Cetuximab as the maintenance treatment, and to provide a new choice for RAS wild-type colorectal cancer patients after advanced first-line chemotherapy.

Timeline

Start
2019-11-28
Primary completion
2021-11-28
Completion
2021-11-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Cetuximab Monoclonal antibody 500 mg/kg Intravenous
Subject Raltitrexed Small molecule 2.5 mg/m2 Intravenous

Indications