Impact of Estradiol on Endothelial Function in Peri-Menopausal Women

Phase 4 Active not recruiting 80 enrolled University of Delaware National Heart, Lung, and Blood Institute (NHLBI) · collab

RandomizedParallel-groupTriple-blindBasic science

Summary

The purpose of this study is to identify the impact of estradiol (E2) on the mechanisms that regulate vascular endothelial function in peri-menopausal (PERI) women. This study is the first step in understanding factors contributing to endothelial dysfunction in women with advancing reproductive age and in response to E2 administration.

Timeline

Start: 2020-10-01
Primary completion: 2026-09-01
Completion: 2026-10-31

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Estradiol	Other / unclassified	0.1 mg	Other

Indications

No indication recorded.