drugset / Trial / NCT04257682
Regional Anesthesia in Total Hip and Knee Arthroplasty
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to test whether the use of Ropivacaine and Mepivacaine are better in terms of effectiveness, cost, and safety than Bupivacaine as regional anesthetics in elective hip or knee replacement surgery.
Timeline
- Start
- 2022-09
- Primary completion
- 2023-02
- Completion
- 2023-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 6.75 mg | Other |
| Comparator | Bupivacaine | Other / unclassified | 7.5 mg | Other |
| Comparator | Bupivacaine | Other / unclassified | 8.25 mg | Other |
| Comparator | Bupivacaine | Other / unclassified | 9 mg | Other |
| Comparator | Mepivacaine | Other / unclassified | 40 mg | Other |
| Comparator | Mepivacaine | Other / unclassified | 45 mg | Other |
| Comparator | Mepivacaine | Other / unclassified | 50 mg | Other |
| Comparator | Mepivacaine | Other / unclassified | 55 mg | Other |
| Comparator | Ropivacaine | Other / unclassified | 9 mg | Other |
| Comparator | Ropivacaine | Other / unclassified | 10 mg | Other |
| Comparator | Ropivacaine | Other / unclassified | 11 mg | Other |
| Comparator | Ropivacaine | Other / unclassified | 12 mg | Other |