drugset / Trial / NCT04272775

A Study of MLN9708 in Japanese Participants With Relapsed and/or Refractory Multiple Myeloma (RRMM)

NCT04272775

Phase 1 Terminated 14 enrolled Takeda
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to evaluate the tolerability, safety, pharmacokinetics (PK) of ixazomib alone or in combination with lenalidomide and dexamethasone (Rd), and antitumor activity of ixazomib in participants with RRMM.

Timeline

Start
2012-06-05
Primary completion
2019-02-15
Completion
2019-02-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 40 mg Oral
Subject Ixazomib Unknown 4 mg Oral
Subject Ixazomib Unknown 5.5 mg Oral
Subject Lenalidomide Other / unclassified 25 mg Oral