drugset / Trial / NCT04273646

Study of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Severe COVID-19

NCT04273646

RandomizedParallel-groupOpen-labelTreatment

Summary

The novel coronavirus pneumonia is a kind of new emerging respiratory infectious disease, characterized by fever, dry cough, and chest tightness, and caused by the infection of the 2019 novel coronavirus (2019-nCoV). In severe cases, there will be rapid respiratory system failure. The novel coronavirus pneumonia is extremely contagious and the disease progresses rapidly. It has become a urgent and serious public health event that threatens human life and health globally. Among them, severe pneumonia caused by novel coronavirus is characterized by extensive acute inflammation of the lungs and the patient is critically ill. At present, there is no effective treatment in clinical practice.Most of them should receive supportive care to help relieve symptoms. For severe cases, treatment should include care to support vital organ functions. This clinical trial is to inspect the safety and efficiency of Human Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) therapy for severe pneumonia patients infected with 2019-nCoV.

Timeline

Start
2020-04-20
Primary completion
2020-06-30
Completion
2022-02-15

Drugs

EvaluationDrugModalityDoseRoute
Subject mesenchymal stem cells Cell therapy 500000 cells/kg Intravenous

Indications