Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment and PSORI-CM01 Granule in Psoriasis Patients

Completed 8 enrolled Guangdong Provincial Hospital of Traditional Chinese Medicine

NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the efficacy and safety of Adipose derived Mesenchymal Stem Cells (AD-MSCs) plus Calpocitriol Ointment and PSORI-CM01 Granule with moderate to severe psoriasis. Any adverse events related to AD-MSCs infusion will be monitored.The primary outcome is the reduction rate of PASI(Psoriasis Area and Severity Index) and treatment response will be computed from PASI before and after treatment.

Timeline

Start: 2020-04-01
Primary completion: 2020-06-17
Completion: 2021-02-03

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Autologous Adipose-Derived Mesenchymal Stromal Cells	Cell therapy	2 cells/kg	Intravenous
Background	Calcipotriol	Small molecule	—	Topical
Background	PSORI-CM01	Unknown	5.5 g	Oral

Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment and PSORI-CM01 Granule in Psoriasis Patients

Summary

Timeline

Drugs

Indications