drugset / Trial / NCT04288700
Evaluation of the Efficacy of Captopril Versus Propranolol and Timolol as a Treatment of Infantile Capillary Hemangioma
RandomizedParallel-groupOpen-labelTreatment
Summary
Is to compare and evaluate the efficacy of oral captopril with oral propranolol, intralesional propranolol injection, and topical Timolol in the treatment of infantile hemangioma and their effect on vascular endothelial growth factor and CD 133.
Timeline
- Start
- 2019-10-01
- Primary completion
- 2020-12-01
- Completion
- 2021-10-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Captopril | Small molecule | 0.3 mg/kg | Oral |
| Comparator | Propranolol | Small molecule | 1 mg/ml | Oral |
| Comparator | Propranolol | Small molecule | 2 mg/kg | Oral |
| Comparator | Timolol | Other / unclassified | 0.5 % | Topical |