drugset / Trial / NCT04292184
Evaluation of Thiosulfate in End Stage Renal Disease and Kidney Transplantation
Phase 1
Completed
18 enrolled
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
RandomizedParallel-groupOpen-labelTreatment
Summary
Kidneys retrieved from deceased donors will be randomized for conventional perfusion (University of Wisconsin: UW) with or without supplementation of thiosulfate, a major H2S metabolite, and transpl anted thereafter. Recipient's renal function will be assessed prospectively to determine if thiosulfate improves allograft function.
Timeline
- Start
- 2021-03-21
- Primary completion
- 2022-11-01
- Completion
- 2022-11-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sodium Thiosulfate | Diagnostic / imaging agent | 500 unknown | Other |