Dexmedetomidine on Tourniquet Induced -Systemic Effects

Summary

Eighty patients were randomly assigned to either control (CON) or dexmedetomidine (DEX) group. DEX group received a loading dose of 0.5 µg/ kg of intravenous dexmedetomidine over 10 minutes, followed by a continuous infusion of 0.5 µg/kg/h until completion of the surgery. CON group received the same calculated volume of normal saline. Pain outcomes, metabolic and coagulative changes after tourniquet application, and after tourniquet release were investigated.

Timeline

Start

2020-02-03

Primary completion

2020-02-10

Completion

2020-03-05

Drugs

Indications