drugset / Trial / NCT04313959

Comparison Erect Spine in Cardiac Surgery

NCT04313959

Phase 3 Unknown 40 enrolled Instituto do Coracao
RandomizedParallel-groupQuadruple-blindPrevention

Summary

Open cardiac surgeries are characterized by the increased use of opioids and longer extubation times, being post-sternotomy pain one of the causes of greater patient discomfort, plexus blockages have been used more frequently given the good results of anatomical studies and case series that are just beginning to be published. however, there is not enough data to convince the scientific community of its advantages, continuing to carry out its performance due to lack of evidence. Dexamethasone also shows an excellent result blocking the inflammatory chain and it was evidenced that it prolongs the time of blockages when used perineurally in the plexus blockages. This study wants to show the improvement of pain in patients who undergo this type of surgery and also show the advantages of a longer blockage, which can reduce use of analgesic and opioids, as well as decrease the time of hospitalization This is a double-blinded, randomized, clinical trial designed to determine the efficacy of spine erector whit dexamethasone gives more duration of the blockage and less pain after cardiac surgery.

Timeline

Start
2022-01-20
Primary completion
2023-02-25
Completion
2023-04-17

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexamethasone Small molecule 5 mg Other
Comparator Ropivacaine Other / unclassified 0.2 % Other
Comparator Ropivacaine Other / unclassified 25 ml Other

Indications