drugset / Trial / NCT04315116
A Drug-drug Interaction Trial of Loperamide Pharmacokinetics Effect on Pyrotinib Maleate
NaSingle-groupOpen-labelBasic science
Summary
The primary objective of the study was to assess the effect of repeated oral doses of Loperamide on the pharmacokinetic profile of a single dose of Pyrotinib Maleate. The secondary objective of the study was to assess the safety of Pyrotinib Maleate given alone versus Fluzoparib coadministered with Loperamide.
Timeline
- Start
- 2020-04-13
- Primary completion
- 2020-04-30
- Completion
- 2020-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Loperamide | Small molecule | 4 mg | Oral |
| Subject | Pyrotinib | Small molecule | — | Oral |
Indications
No indication recorded.