Potassium Chloride in Out-of-hospital Cardiac Arrest Due to Refractory Ventricular Fibrillation

Phase 2 Withdrawn Assistance Publique - Hôpitaux de Paris URC-CIC Paris Descartes Necker Cochin · collab

NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate, in patients presenting with out-of-hospital cardiac arrest (OHCA) by ventricular fibrillation, refractory to 3 external electric shocks, the efficacy of a direct intravenous injection of 20 mmol KCl on their survival at hospital arrival.

Timeline

Start: 2023-12
Primary completion: 2024-12
Completion: 2024-12

Outcome

Outcome not reported

Stopped: “As the inclusion period in the study has ended and regulatory authorizations have expired on 26/12/2023, with no inclusions conducted.”

Publications

Jouffroy R, Ecollan P, Chollet-Xemard C, Prunet B, Elie C, Treluyer JM, Vivien B. Evaluation of the effectiveness of potassium chloride in the management of out-of hospital cardiac arrest by refractory ventricular fibrillation: Study protocol of the POTACREH study. PLoS One. 2023 Apr 12;18(4):e0284429. doi: 10.1371/journal.pone.0284429. eCollection 2023.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Potassium Chloride	Small molecule	20 mmol	Intravenous