Drugs / Potassium Chloride
Potassium Chloride
also known as
KCl · B1653 · Chloride (as potassium) · Diffu-k · Duro-k · E 508 · INS NO.508 · INS-508 · +54 more
Regulatory milestones approvals, filings & regulatory actions · 3 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | KLOR-CON | — | 1992-06-26 | fda.gov ↗ |
| Label expansion | US (FDA) | MICRO-K | — | 1984-05-14 | fda.gov ↗ |
| Approved | US (FDA) | THAM | — | 1965-12-16 | fda.gov ↗ |
Trials 12
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials · 1 missed | ||||||
| Phase 2 | NCT04316611 | Dec 2023 → Dec 2024 | cardiac arrest | Assistance Publique - Hôpitaux de Paris | Withdrawn | No outcome recorded |
| Phase 2 | NCT02236598 | Jan 2015 → Feb 2016 | potassium deficiency | Duke University | Completed | Missed primary |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT04802785 | Jun → Jul 2021 | — | Dinara Zhumanbayeva | Unknown | No outcome recorded |
| Phase 32 trials · 1 missed | ||||||
| Phase 3 | NCT03106922 | Apr 2016 → Jul 2020 | — | Alfasigma S.p.A. | Unknown | No outcome recorded |
| Phase 3 | NCT00091507 | Nov 2006 → Aug 2011 | congestive heart failure, intermediate coronary syndrome, myocardial infarction | Tufts Medical Center | Completed | Missed primary |
| Phase 45 trials · 1 missed | ||||||
| Phase 4 | NCT05365477 | Aug 2022 → Sep 2025 | nephrolithiasis | Vanderbilt University Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT02380157 | Mar 2015 → Dec 2016 | hypertensive disorder | Glostrup University Hospital, Copenhagen | Completed | No outcome recorded |
| Phase 4 | NCT02015962 | Oct 2013 → May 2014 | potassium deficiency | Aga Khan University | Unknown | No outcome recorded |
| Phase 4 | NCT01818583 | Mar 2013 → Nov 2017 | atrial fibrillation, atrial flutter | Diakonhjemmet Hospital | Completed | Missed primary |
| Phase 4 | NCT02653560 | Sep 2012 → Jan 2015 | hypertensive disorder | University of Texas Southwestern Medical Center | Completed | No outcome recorded |
| Phase not applicable2 trials | ||||||
| — | NCT02982356 | Jan 2017 → Dec 2019 | chromosomal disorder, pregnancy disorder | Shanghai First Maternity and Infant Hospital | Unknown | No outcome recorded |
| — | NCT00224939 | Jul 2002 → Dec 2006 | hypertensive disorder | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Terminated | No outcome recorded Stop: Enrollment |
| Comparator or background therapy23 trials | ||||||
| Phase 1/2 | NCT01074918 Comparator | Sep 2009 → Sep 2012 | hypertensive disorder | University of Texas Southwestern Medical Center | Withdrawn | No outcome recorded Stop: Enrollment |
| Phase 2 | NCT07238400 Comparator | Mar 2026 → Mar 2029 expected | hypertensive disorder | Massachusetts General Hospital | Recruiting | No outcome recorded |
| Phase 2 | NCT05138575 Comparator | Jan 2022 → May 2027 expected | diastolic heart failure | University of Pennsylvania | Recruiting | No outcome recorded |
| Phase 2 | NCT03483051 Comparator | May 2018 → Mar 2019 | aortic valve stenosis | University of Pennsylvania | Completed | No outcome recorded |
| Phase 2 | NCT02450773 Background | Aug 2015 → May 2022 | hypertensive disorder | Indiana University | Withdrawn | No outcome recorded |
| Phase 2 | NCT01516138 Comparator | Feb 2012 → Mar 2013 | — | Xijing Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT00913796 Comparator | Dec 2007 → Mar 2010 | bone disorder, metabolic acidosis, mineral metabolism disease | University of Zurich | Completed | No outcome recorded |
| Phase 2/3 | NCT07469722 Background | Mar 2026 → Jan 2028 expected | congestive heart failure | Hospital de Clinicas de Porto Alegre | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT00241839 Comparator | Aug 2005 → May 2011 | heart disorder, hypertensive disorder | University of Florida | Completed | No outcome recorded |
| Phase 4 | NCT05898022 Background | Aug 2023 → Jul 2025 | bronchopulmonary dysplasia | Children's Hospital Medical Center, Cincinnati | Completed | No outcome recorded |
| Phase 4 | NCT04519164 Comparator | Dec 2020 → Sep 2025 | hypertensive disorder, metabolic syndrome X | Brigham and Women's Hospital | Completed | No outcome recorded |
| Phase 4 | NCT05076604 Comparator | Mar 2019 → Jun 2023 | aortic valve disorder, mitral valve disorder | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 4 | NCT02481518 Background | Mar 2015 → Mar 2016 | acute kidney injury | Mahidol University | Completed | No outcome recorded |
| Phase 4 | NCT02082717 Background | Feb 2014 → Aug 2018 | potassium deficiency | Baptist Health South Florida | Terminated | No outcome recorded |
| Phase 4 | NCT01085071 Comparator | Jun 2009 → Dec 2011 | — | University Medical Center Groningen | Completed | No outcome recorded |
| Phase 4 | NCT00718068 Comparator | Oct 2008 → Sep 2009 | cardiac rhythm disease, potassium deficiency | The Queen Elizabeth Hospital | Completed | No outcome recorded |
| — | NCT07451561 Comparator | Mar 2026 → Mar 2027 expected | — | Sohag University | Not yet recruiting | No outcome recorded |
| — | NCT05464966 Background | Jun 2022 → May 2023 | — | Yangzhou University | Completed | No outcome recorded |
| — | NCT05839574 Comparator | Jan 2021 → Dec 2022 | uterine disorder | Jagiellonian University | Completed | No outcome recorded |
| — | NCT01760174 Comparator | Jan → Dec 2016 | neuropathy, painful | Aalborg University Hospital | Withdrawn | No outcome recorded |
| — | NCT02665117 Comparator | Jan 2015 → Nov 2022 | hypertensive disorder | University of Texas Southwestern Medical Center | Completed | No outcome recorded |
| — | NCT01575041 Comparator | Jan → Jul 2012 | hypertensive disorder | Wageningen University | Completed | No outcome recorded |
| — | NCT01225159 Background | Sep 2008 → Mar 2009 | hypoglycemia, nosocomial infection | Prince of Songkla University | Terminated | No outcome recorded |
Press releases naming this drug 4 releases
| Date | Issuer | Release |
|---|---|---|
| 2020-06-01 | Alturix | ALTURiX Acquires Slow-K ® UK Rights alturix.com ↗ |
| 2019-07-01 | Upsher-Smith Laboratories | Upsher-Smith to Commercialize Klor-Con and Potassium Chloride Product Families upsher-smith.com ↗ |
| 2017-11-28 | Upsher-Smith Laboratories | Upsher-Smith Launches Klor-Con Powder (potassium chloride) for Oral Solution upsher-smith.com ↗ |
| 2016-08-10 | Lupin Limited | Lupin Receives FDA Approval for Generic Klor-Con® Extended-Release Tablets lupin.com ↗ |
Evidence & citations 65 cited values
Every value below carries the sentence it was read from. 39 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Potassium Chloride | “A separate mixture of glucose 25% (A.N.B Laboratories, Thailand) 50 mL, potassium chloride (Nida pharma, Thailand) 20 mEq and magnesium sulfate (Atlantic, Thailand) 2 gm was infused” NCT01225159 ↗34“For calcium \>250mg male, \>200mg female: indapamide 1.25mg and potassium chloride 20mEq. At 1 month if persistent, then increase to indapamide 2.5mg and potassium chloride 20mEq.” NCT05365477 ↗ “Pre loading fluid with Magnesium sulphate 16 milliequivalent plus potassium chloride 20 milliequivalent in Normal saline 500 ml IV drip in 4 hours before Cisplatin administration” NCT02481518 ↗ “We sought to determine the effects of potassium chloride (KCl) supplements, at a commonly prescribed dose, on measures of potassium and glucose metabolism.” PMID 29092881 ↗ Nov 2017 “glucose-insulin-potassium (GIK) consists of 20% glucose (200 g/L), 66.7 U/L regular insulin and 80 mmol/L potassium chloride (KCl).” NCT01516138 ↗ “Potassium Chloride (provided by Microz, Geleen, Netherlands): 8 capsules per day which equals a potassium intake of 3 grams.” NCT01575041 ↗ “Sachet B: sodium citrate 1.863 g, anhydrous citric acid 0.813 g, sodium chloride 0.730 g, potassium chloride 0.370 g;” NCT03106922 ↗ “Potassium will be given at dose of 20-80 meq/L of potassium chloride to maintain serum potassium at 3.5 to 4.5 meq/L.” NCT07451561 ↗ “Isotonic potassium chloride, 10-25 ml in each transversus abdominis catheter, depending on patient weight.” NCT01760174 ↗ “747 mL Baxter Cardioplegia Solution 3.4 mL Potassium Chloride 2 meq/ml (6.75 meq) 750.4 mL total volume” NCT05076604 ↗ “In one-liter: Dextrose 30% + 80 mEq Potassium Chloride + 50 units Regular Insulin” NCT00091507 ↗ |
| Known as | B1653 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Chloride (as potassium) | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Diffu-k | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Duro-k | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | E 508 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | INS NO.508 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | INS-508 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | K-contin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | K-dur 20 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | K-lease | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | K-tab | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Kaleorid | “Kaleorid, 750mg (trade name), Potassium chloride (active substance)” NCT02380157 ↗ |
| Known as | Kaleorid lp | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Kali muriaticum | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Kalii chloridum | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Kaon cl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Kaon cl-10 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Kay-cee-l | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | KCl | “patients with ROAF or atrial flutter and plasma-potassium ≤4.0 mmol/L presenting between April 2013 and November 2017 were randomized to receive potassium chloride (KCl)...” PMID 31986288 ↗ Dec 20194“By extension, direct intravenous administration of potassium chloride (KCl) has been shown to convert VF, resulting in return to a hemodynamically efficient organized heart...” PMID 37043520 ↗ Apr 2023 “We sought to determine the effects of potassium chloride (KCl) supplements, at a commonly prescribed dose, on measures of potassium and glucose metabolism.” PMID 29092881 ↗ Nov 2017 “glucose-insulin-potassium (GIK) consists of 20% glucose (200 g/L), 66.7 U/L regular insulin and 80 mmol/L potassium chloride (KCl).” NCT01516138 ↗ “Potassium chloride (KCl)” NCT03483051 ↗ |
| Known as | Klor-con | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Klor-con 10 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Klor-con 10meq | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Klor-con 8 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Klor-Con M10 | “K-supplement- Klor-Con® M10 is an immediately dispersing extended-release oral dosage form of potassium chloride containing 750 mg of microencapsulated potassium chloride,...” NCT02236598 ↗ |
| Known as | Klor-con m15 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Klor-con m20 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Kloref | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Kloref-s | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Klotrix | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Leo k | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Micro k | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Micro-k 10 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Micro-k ls | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Neobakasal | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | NSC-77368 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Pokonza | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Pot chlor (pot 12mmol) | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Pot chlor strong | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium (as chloride) | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride (42kcl) | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of colyte | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of golytely | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of halflytely | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of moviprep | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of navstel | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of nulytely | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of plenvu | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of procalamine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of suclear | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of suflave | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of sutab | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of tham-e | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride component of tis-u-sol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | POTASSIUM CHLORIDE K 42 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium chloride potassium-42 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Potassium k-42 chloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Sando-k | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Slow-k | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Sterile Potassium Chloride Concentrate | “Drug: Sterile Potassium Chloride Concentrate” NCT00718068 ↗ |
| Known as | Sylvine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Sylvite | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Known as | Ten-k | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200731 ↗ |
| Modality | Small molecule | — CHEMBL1200731 ↗ |
| Route | Intravenous | “Intravenous solution” NCT00091507 ↗ |