Benefits of GIK in Cardiac Surgery Patients

Phase 2 Unknown 930 enrolled Xijing Hospital

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to evaluate the effects of modified glucose - insulin - potassium (GIK) therapy in cardiac surgery patients undergoing cardiopulmonary bypass (CPB).

Timeline

Start: 2012-02
Primary completion: 2013-03
Completion: 2022-02

Publications

Zhao K, Zhang Y, Li J, Cui Q, Zhao R, Chen W, Liu J, Zhao B, Wan Y, Ma XL, Yu S, Yi D, Gao F. Modified Glucose-Insulin-Potassium Regimen Provides Cardioprotection With Improved Tissue Perfusion in Patients Undergoing Cardiopulmonary Bypass Surgery. J Am Heart Assoc. 2020 Mar 17;9(6):e012376. doi: 10.1161/JAHA.119.012376. Epub 2020 Mar 10.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Glucose	Unknown	—	Intravenous
Comparator	Insulin	Protein / enzyme biologic	—	Intravenous
Comparator	Potassium Chloride	Small molecule	—	Intravenous

Indications

No indication recorded.