Empiric Versus Selective Prevention Strategies for Kidney Stone Disease

Summary

The aims of this study are to 1) Conduct a randomized clinical trial of selective versus empiric diet plus pharmacologic therapy in high-risk stone formers and 2) Determine adverse effects from, and adherence to selective and empiric strategies.

Timeline

Start

2022-08-04

Primary completion

2025-09-26

Completion

2026-03-31

Publications

• Widmer A, Lee A, Koyama T, Goldfarb DS, Hsi RS, Silver HJ. Targeted versus empiric approach for prevention of recurrent kidney stones: Insights on diet therapy from a randomized trial. Clin Nutr. 2026 Aug 11;65:106754. doi: 10.1016/j.clnu.2026.106754. Online ahead of print.

Drugs

Indications