drugset / Trial / NCT04321551
Hormone Secretion in Transgender Males
NaSingle-groupOpen-labelOther
Summary
Aim 1 utilizes prospective clinical studies in TGN to test the hypothesis that prolonged exogenous androgens alter menstrual cyclicity by inhibiting gonadotropin secretion, steroid hormone release, and ovulation. We will utilize a clinical trial of TRT to evaluate T suppression of ovarian follicle and hormone dynamics (Aim 1A) and LH pulsatility (Aim 1B).
Timeline
- Start
- 2023-07-01
- Primary completion
- 2028-06-30
- Completion
- 2028-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Letrozole | Other / unclassified | 2.5 mg | Oral |
| Subject | Testosterone Cypionate | Small molecule | 50 mg | Intramuscular |
Indications
No indication recorded.