drugset / Trial / NCT04322955

CYTO Reductive Surgery in Kidney Cancer Plus Immunotherapy and Targeted Kinase Inhibition

NCT04322955 ↗

Phase 2 Active not recruiting 38 enrolled Mark Stein Bristol-Myers Squibb · collabExelixis · collab
NaSequentialOpen-labelTreatment

Summary

The purpose of this study is to determine if the use of immunotherapy nivolumab and the targeted therapy cabozantinib prior to removal of the kidney, will increase the number subjects who are without any visible kidney cancer in their body at some point during the course of treatment.

Timeline

Start
2020-06-22
Primary completion
2027-05
Completion
2028-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Cabozantinib Small molecule 40 mg Oral
Subject Nivolumab Monoclonal antibody 480 mg Intravenous

Indications