drugset / Trial / NCT04337606

Chidamide in Combination With Decitabine in Non-Hodgkin's Lymphoma Relapsed After Chimeric Antigen Receptor

NCT04337606

Phase 1/2 Unknown 100 enrolled Chinese PLA General Hospital
RandomizedSingle-groupOpen-labelTreatment

Summary

This is a Phase I/II clinical trial for patients with r/r Non-Hodgkin's Lymphoma relapsed after chimeric antigen receptor T cells infusion. The purpose is to evaluate the safety and efficacy of the treatment with chidamide in combination with decitabine.

Timeline

Start
2020-04-04
Primary completion
2024-04-04
Completion
2026-04-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Camrelizumab Monoclonal antibody 200 mg
Subject Decitabine Small molecule 10 mg
Subject Tucidinostat Small molecule 20 mg Oral

Indications