drugset / Trial / NCT04341311
Phase I Study of Marizomib + Panobinostat for Children With DIPG
Phase 1
Terminated
4 enrolled
Dana-Farber Cancer Institute
Celgene Corporation · collabSecura Bio, Inc. · collab
Non-randomizedSingle-groupOpen-labelTreatment
Summary
This research study is evaluating the safety, tolerability and preliminary efficacy of the drugs marizomib and panobinostat in pediatric patients with diffuse intrinsic pontine glioma (DIPG). The names of the study drugs involved in this study are: * Marizomib * Panobinostat
Timeline
- Start
- 2020-08-10
- Primary completion
- 2024-02-14
- Completion
- 2024-02-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Marizomib | Small molecule | — | Intravenous |
| Subject | Panobinostat | Small molecule | — | Oral |