drugset / Trial / NCT04341402

Systemic Uptake of Diclofenac Sodium in Combination With Miconazole as Antifungal Nail Gel When Applied Daily With Monitoring of Hepatic and Renal Enzymes, and Serum Levels of Diclofenac 12 Hours After Application, and at 3 and 6 Months Study

NCT04341402

Phase 2 Unknown 30 enrolled William N Handelman
NaSingle-groupOpen-labelTreatment

Summary

Study evaluates these take of diclofenac sodium when used in conjunction with miconazole and urea as a topical antifungal nail gel treatment for onychomycosis. All of the patient's will be treated with the active formula and blood levels of diclofenac sodium tested for as well as monitoring of hepatic and renal functions

Timeline

Start
2020-05-01
Primary completion
2021-03-31
Completion
2021-05-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Diclofenac Other / unclassified 1 % Topical
Subject Miconazole Small molecule 3 % Topical
Subject drug: urea Unknown 40 % Topical

Indications