drugset / Trial / NCT04355520

A Study of TQ-B3525 Tablets Combined With Fulvestrant Injection in Subjects With HR-positive, HER2-negative and PIK3CA Mutation Advanced Breast Cancer

NCT04355520

Phase 1/2 Unknown 42 enrolled Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

This is a open-label, multicenter phase Ib study to evaluate safety and efficacy of TQ-B3525 tablets combined with fulvestrant injection in subjects with HR-positive, HER2-negative and PIK3CA mutation advanced breast cancer.

Timeline

Start
2020-07
Primary completion
2021-06
Completion
2021-09

Drugs

EvaluationDrugModalityDoseRoute
Subject TQ-B3525 Small molecule 20 mg Oral
Subject TQ-B3525 Small molecule 30 mg Oral
Background Fulvestrant Small molecule 500 mg Intravenous