drugset / Trial / NCT04359966

Prospective Randomised Trial of First and Second Line Treatments of RCT of First and Second Line H Pylori Treatments in Slovenia

NCT04359966 ↗

RandomizedParallel-groupOpen-labelTreatment

Summary

Study is prospective randomised multicentric. The primary objective of the study is to compare the efficacy of two first-line therapy regimens and two second-line therapy regimens (ie, after failure of first-line treatment) in patients with H. pylori infection. The secondary objective of the study is to determine the primary resistance of H. pylori to antibiotics in Slovenia.

Timeline

Start
2020-05-10
Primary completion
2023-05-31
Completion
2023-09-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Amoxicillin Other / unclassified 500 mg —
Comparator Amoxicillin Other / unclassified 1000 mg —
Comparator Bismuth subcitrate Unknown 120 mg —
Comparator Clarithromycin Small molecule 500 mg —
Comparator Esomeprazole Small molecule 40 mg —
Subject Levofloxacin Small molecule 500 mg —
Comparator Metronidazole Small molecule 400 mg —