drugset / Trial / NCT04359966

Prospective Randomised Trial of First and Second Line Treatments of RCT of First and Second Line H Pylori Treatments in Slovenia

NCT04359966

RandomizedParallel-groupOpen-labelTreatment

Summary

Study is prospective randomised multicentric. The primary objective of the study is to compare the efficacy of two first-line therapy regimens and two second-line therapy regimens (ie, after failure of first-line treatment) in patients with H. pylori infection. The secondary objective of the study is to determine the primary resistance of H. pylori to antibiotics in Slovenia.

Timeline

Start
2020-05-10
Primary completion
2023-05-31
Completion
2023-09-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Amoxicillin Other / unclassified 500 mg
Comparator Amoxicillin Other / unclassified 1000 mg
Comparator Clarithromycin Small molecule 500 mg
Comparator Esomeprazole Small molecule 40 mg
Subject Levofloxacin Small molecule 500 mg
Comparator Metronidazole Small molecule 400 mg
Comparator bismuth subcitrate Unknown 120 mg