drugset / Trial / NCT04371523

Hydroxychloroquine to Prevent COVID-19 Disease Amongst Healthcare Workers

NCT04371523 ↗

RandomizedParallel-groupQuadruple-blindPrevention

Summary

The objectives of PROVIDE are to: 1. Determine if prophylactic once weekly hydroxychloroquine reduces the incidence of conversion from SARS-2-CoVnasopharyngeal swab negative to positive 2. To determine if weekly prophylactic hydroxychloroquine reduced the severity of COVID-19 symptoms 3. To determine the safety of taking weekly prophylactic hydroxychloroquine

Timeline

Start
2020-05-01
Primary completion
2020-07-31
Completion
2020-08-30

Outcome

Outcome not reported

Stopped: “Study was not initiated due to evidence becoming available that did not support the use of hydroxychloroquine in this population, with potential risk of added harm”

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydroxychloroquine Small molecule 400 mg Oral

Indications