drugset / Trial / NCT04376268

Comparison of the Efficacy of Boric Acid Mouthwashes in Different Concentrations

NCT04376268

Phase 4 Unknown 80 enrolled Yuzuncu Yil University
RandomizedFactorialQuadruple-blindPrevention

Summary

Surgical removal of impacted third molars is one of the most frequent procedures carried out in the oral and maxillofacial surgery clinics. There are a varying range of postoperative complications including pain, edema and swelling. Antibiotics, analgesics and mouthwashes are usually prescribed for the treatment of these complications. Patients undergoing impacted third molar surgery are frequently prescribed chlorhexidine mouthwashes with/without benzydamine hydrochloride. However, there has been a search for alternatives with anti-inflammatory, antibacterial and analgesic properties as part of the oral care routine following surgical removal of impacted third molars. Thus, this multicenter study was aimed to evaluate the effects of chlorhexidine mouthwashes with different boric acid concentrations (%0.1, %0.5, %1, %1.5, %2 and %2.5), and boric acid mouthwash on the postoperative complications and compared with chlorhexidine mouthwash after the removal of impacted wisdom teeth.

Timeline

Start
2019-01-15
Primary completion
2023-11-15
Completion
2023-12-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Chlorhexidine Small molecule 15 ml