drugset / Trial / NCT04414800

Intranasal Ketamine Versus Intranasal Fentanyl

NCT04414800

Phase 3 Completed 125 enrolled Isfahan University of Medical Sciences
RandomizedParallel-groupDouble-blindTreatment

Summary

Abstract Background: Given the inadequate control of pain in patients with injury that refer to the emergency departments, the rapid onset of action of intranasal administration in pain management, and the avoidance of administering opioid medications, the present study aimed at evaluating the effect of intranasal ketamine versus intranasal fentanyl on pain management in isolated traumatic patients Materials and Methods: The current study was performed on 125 patients that were divided into the following three groups: control group (n = 41), 1 mg/kg intranasal ketamine group (n = 40), and 1μg/kg intranasal fentanyl group (n = 44). Then pain scores, HR, RR, BP, and SaO2 were recorded at baseline, 5, 10, 15, 30, and 40 minutes after the intervention.

Timeline

Start
2017-04-01
Primary completion
2018-03-20
Completion
2018-04-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Fentanyl Other / unclassified 1 ug/kg Intranasal
Comparator Ketamine Small molecule 1 mg/kg Intranasal

Indications

No indication recorded.