drugset / Trial / NCT04442919
Influence of METHoxyflurane on ANtiplatelet Effect of Ticagrelor in Patients With Unstable Angina Pectoris
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate differences in the pharmacokinetics and pharmacodynamics of ticagrelor and its active metabolite in patients who received ticagrelor followed with methoxyflurane versus ticagrelor followed with morphine or ticagrelor alone due to unstable angina pectoris
Timeline
- Start
- 2020-06-01
- Primary completion
- 2024-01-31
- Completion
- 2024-02-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methoxyflurane | Small molecule | 3 mg | Inhaled |
| Comparator | Morphine | Other / unclassified | 5 mg | Intravenous |
| Comparator | Ticagrelor | Small molecule | 180 mg | — |