drugset

drugset / Trial / NCT04454879

Different Doses of Roxadustat Treatment for Anemia in Peritoneal Dialysis Patients

NCT04454879 ↗

Phase 4 Completed 100 enrolled Peking University First Hospital Beijing Haidian Hospital · collab Beijing Hospital of Traditional Chinese Medicine · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

A multi-center, randomized, controlled study to evaluate the effect of different doses of roxadustate on hemoglobin target-met in peritoneal dialysis patients

Timeline

Start: 2020-07-01
Primary completion: 2021-04-03
Completion: 2021-08-03

Publications

Yang Z, Ma T, Xu X, Fu G, Zhao J, Xu Y, Yang B, Song D, Zhu S, Lv J, Dong J. Randomized Study on the Efficacy of Standard Versus Low Roxadustat Dose for Anemia in Patients on Peritoneal Dialysis. Kidney Int Rep. 2021 Dec 27;7(3):455-464. doi: 10.1016/j.ekir.2021.12.025. eCollection 2022 Mar.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Roxadustat	Small molecule	50 mg	Oral
Subject	Roxadustat	Small molecule	70 mg	Oral
Subject	Roxadustat	Small molecule	90 mg	Oral
Subject	Roxadustat	Small molecule	100 mg	Oral
Subject	Roxadustat	Small molecule	110 mg	Oral
Subject	Roxadustat	Small molecule	120 mg	Oral

Indications