drugset / Trial / NCT04459663
JS001 Combination Therapy in NSCLC Negative Driving Gene After First-line Chemotherapy.
NaSingle-groupOpen-labelTreatment
Summary
This is a phase II, open, single-center clinical study to evaluate the efficacy and safety of JS001 combined with Axitinib in the treatment of advanced non-small cell lung cancer without activated EGFR mutation, ALK fusion and ROS fusion after or during first-line chemotherapy. About 50 subjects will be included in this study and will be treated with JS001 combined with acitinib. Each cycle is 21 days.
Timeline
- Start
- 2020-08-31
- Primary completion
- 2023-09-30
- Completion
- 2023-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Axitinib | Small molecule | 5 mg | Oral |
| Subject | Toripalimab | Monoclonal antibody | 240 mg | Intravenous |