drugset / Trial / NCT04464239
A Single Ascending and Repeated Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TS-142 in Healthy Participants
RandomizedParallel-groupDouble-blindTreatment
Summary
This is a study to evaluate the safety, tolerability, and pharmacokinetics of single oral doses of TS-142 compared to placebo and of a single repeated dose compared to placebo in healthy volunteers. This Phase I study is composed of two parts; Part A (Single Ascending Dose) and Part B (Repeated Dose). The study employs a randomized, double-blind, placebo-controlled, parallel group design to evaluate the single and repeat-dose safety and pharmacokinetics of TS-142 in healthy participants.
Timeline
- Start
- 2020-09-14
- Primary completion
- 2021-01-21
- Completion
- 2021-01-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | TS-142 | Small molecule | 10 mg | Oral |
| Subject | TS-142 | Small molecule | 20 mg | Oral |
| Subject | TS-142 | Small molecule | 30 mg | Oral |
Indications
No indication recorded.