drugset / Trial / NCT04470310

Glimepiride, Alogliptin and Alogliptin+Pioglitazone Combination

NCT04470310

Phase 4 Unknown 99 enrolled Seoul National University Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

* This trial is a three-armed, open label, random assignment trial. * The research subjects are patients who are first starting their treatment or patients who have failed with the metformin treatment and are changing their medication. They will be assigned to one of the following treatment groups: the glimepiride monotherapy treatment group, the alogliptin monotherapy treatment group, and the alogliptin - pioglitazone combination therapy treatment group * This trial is a prospective trial which will conduct surveys 6 times over the course of the 6 months in which each treatment group is administered drugs (Week -2, Baseline, Week 4, Week 12, Week 24, follow-up safety survey). * This trial is a multicenter clinical trial which will be conducted at more than 5 general hospital medical institutions in the vicinity of the capital.

Timeline

Start
2015-12-31
Primary completion
2019-05-20
Completion
2021-08-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Alogliptin Unknown 25 mg Oral
Comparator Glimepiride Small molecule 2 mg
Comparator Pioglitazone Small molecule 15 mg Oral