Effect of Metformin on Non PCO Women Undergoing IVF/ICSI

Summary

400 Patients will be randomly assigned into two groups after informed consent from every patient. They will be classified into 2 groups: Group A ( involves 200 patients ) will receive metformin 850 mg twice daily along the cycle of Intra-cytoplasmic sperm injection (ICSI) Group B ( involve 200 patients) will not receive metformin. They will undergo a cycle of ICSI. Primary outcome of this trial is to detect occurrence of Ovarian Hyper-stimulation Syndrome (OHSS) , while secondary outcomes include quality \& number of retrieved follicles fertilization rate ,ongoing pregnancy rate \& endometrial thickness.

Timeline

Start

2020-07-28

Primary completion

2020-11-27

Completion

2020-11-27

Drugs

Indications