Misoprostol With Mechanical Dilation Versus Oxytocin With Mechanical Dilation for High-risk Pregnancy Inductions

NCT04492072 ↗

Completed 150 enrolled Thomas Jefferson University

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to specifically investigate whether oxytocin and mechanical dilation decreases the rate of cesarean section compared to misoprostol and mechanical dilation for pregnancies at risk of fetal compromise

Timeline

Start: 2020-08-17
Primary completion: 2022-05-26
Completion: 2022-05-26

Publications

Al-Hafez L, Khanuja K, Mendez-Figueroa H, Al-Kouatly HB, Mascio DD, Chauhan SP, Berghella V. Misoprostol with balloon vs oxytocin with balloon in high-risk pregnancy induction: a randomized controlled trial. Am J Obstet Gynecol MFM. 2023 Dec;5(12):101175. doi: 10.1016/j.ajogmf.2023.101175. Epub 2023 Oct 6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Misoprostol	Other / unclassified	50 ug	Oral
Subject	Oxytocin	Peptide	2 unknown	—

Indications

No indication recorded.