drugset / Trial / NCT04495140
Study To Characterize Mass Balance, Absolute Bioavailability, Fraction Absorbed And Pharmacokinetics Of 14C PF-06882961
Non-randomizedCrossoverOpen-labelBasic science
Summary
This study is a Phase 1, open-label, non-randomized, 2-period, fixed sequence study to characterize the metabolic profile and routes of excretion of oral \[14C\]PF-06882961 and to evaluate the absolute oral bioavailability of PF-06882961 and fraction absorbed of \[14C\]PF-06882961 in reference to intravenous \[14C\]PF-06882961 in healthy male participants.
Timeline
- Start
- 2020-07-22
- Primary completion
- 2020-10-15
- Completion
- 2020-10-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Danuglipron | Small molecule | 100 ug | Oral |
| Subject | Danuglipron | Small molecule | 50 mg | Oral |
Indications
No indication recorded.