drugset / Trial / NCT04501718

Apatinib Combined with Temozolomide and Etoposide Capsules in the Treatment of Recurrent Medulloblastoma in Children

NCT04501718 ↗

Phase 2 Recruiting 44 enrolled Beijing Sanbo Brain Hospital
NaSingle-groupOpen-labelTreatment

Summary

This study is a prospective single-center clinical study, which aims to observe and evaluate the efficacy and safety of apatinib combined with temozolomide and oral etoposide in the treatment of recurrent medulloblastoma in children.

Timeline

Start
2020-10-28
Primary completion
2025-08-31
Completion
2025-08-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Etoposide Small molecule — Oral
Subject Rivoceranib Small molecule 250 mg Oral
Subject Temozolomide Small molecule — —

Indications