drugset / Trial / NCT04508634

Treating Obese PCOS Patients With LSG vs. Met

NCT04508634 ↗

Phase 4 Unknown 90 enrolled Shanghai 10th People's Hospital
Non-randomizedSingle-groupOpen-labelTreatment

Summary

Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with a prevalence of 5% to 15% in premenopausal women. Patients with PCOS presents as abnormal menstruation, ovulation disorders and/or hyperandrogenemia, and often accompanied by insulin resistance and other metabolic abnormalities. Sleeve gastrectomy was an effective threapy for severe obesity patients. This study will evaluate the clinical efficacy of sleeve gastrectomy for obese patients with PCOS. Mealwhile, the specific mechanism of sleeve gastrectomy for improving obese patients with PCOS will be explored through multi-group analysis.

Timeline

Start
2020-11-01
Primary completion
2024-09-01
Completion
2024-09-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Metformin Small molecule 1000 mg —