drugset / Trial / NCT04509414

Intranasal Dexmedetomidine for Deep-sedated Pediatric Dental Patients

NCT04509414 ↗

Phase 4 Completed 100 enrolled Peking University
RandomizedParallel-groupQuadruple-blindPrevention

Summary

It is important to choose an appropriate analgesia/sedation technique in pediatric dental treatment. Premedication combined with intravenous anesthesia is often used in deep sedation technique for pediatric dental treatment and it's a routine in most hospitals. Deep sedation has its unique advantages such as avoiding the airway damage with an enhanced recovery. Dexmedetomidine is suitable for intranasal mucosal administration as a premedication drug. It has been proved with several beneficial characteristics in other clinical procedures. This study intends to further explore the characteristics of nasal dexmedetomidine as premedication in pediatric oral treatment under deep sedation.

Timeline

Start
2020-04-10
Primary completion
2022-05-01
Completion
2022-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 2 ug/kg Intranasal
Comparator Midazolam Small molecule 0.2 mg/kg Intranasal

Indications

No indication recorded.