drugset / Trial / NCT04510584
Maintenance Treatment With Bevacizumab and Atezolizumab for Ovarian Cancer
NaSingle-groupOpen-labelTreatment
Summary
This study is being done to look at the combination of the drugs atezolizumab and bevacizumab as a maintenance treatment (treatment given after the main treatment to keep the cancer from coming back or worsening) following standard therapy in patients with high grade ovarian, fallopian tube, or primary peritoneal cancer with a mutation (change) in a gene called TP53. Genes are molecules in the body that are made up of deoxyribonucleic acid (DNA) and control how the body's cells behave.
Timeline
- Start
- 2021-07-16
- Primary completion
- 2023-02-22
- Completion
- 2023-02-22
Outcome
Outcome not reported
Stopped (Enrollment): “19 patients screenfailed, stopping recruitment before first patient enrollment to analyze pilot results from screening samples.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atezolizumab | Monoclonal antibody | 1200 mg | Intravenous |
| Subject | Bevacizumab | Monoclonal antibody | 15 mg/kg | Intravenous |