drugset / Trial / NCT04513808

Total Intravenous Anesthesia and Recurrence Free Survival

NCT04513808

Phase 3 Recruiting 1614 enrolled The Cleveland Clinic
RandomizedParallel-groupDouble-blindTreatment

Summary

The investigators propose to compare recurrence-free survival in patients having potentially curative (Stages 1-3) surgery for esophageal cancer who will be randomly assigned to propofol-based total intravenous anesthesia or sevoflurane-based balanced general anesthesia.

Timeline

Start
2020-08-15
Primary completion
2025-12
Completion
2027-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Propofol Small molecule Intravenous
Comparator Sevoflurane Other / unclassified Intravenous

Indications