Relapse in Previously Irradiated Prostate Bed : Stereotactic Ablative Reirradiation Potentiated by Metformin

Summary

This phase I/II escalation dose study is assessing the efficacy of the recommended dose of stereotactic re-irradiation (SBRT) of relapses within the prostatectomy bed, potentiated by metformin

Timeline

Start

2020-11-17

Primary completion

2031-11

Completion

2031-11

Publications

• Joly A, Blanc Lapierre A, Rio E, Vaugier L, Supiot S, Guimas V. REPAIR_GETUG P16 relapse in previously irradiated prostate bed: a phase I/II study of stereotactic ablative reirradiation potentiated by a metformine study protocol. BMJ Open. 2025 Jul 24;15(7):e100031. doi: 10.1136/bmjopen-2025-100031.

Drugs

Indications