drugset / Trial / NCT04540705

A Study to Compare Bempegaldesleukin (BEMPEG: NKTR-214) Combined With Nivolumab and Tyrosine Kinase Inhibitor (TKI) to Nivolumab and TKI Alone in Participants With Previously Untreated Kidney Cancer That is Advanced or Has Spread

NCT04540705

Phase 1 Completed 30 enrolled Bristol-Myers Squibb Nektar Therapeutics · collab
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is in Part 1, to determine the safety of nivolumab, bempegaldesleukin (BEMPEG: NKTR-214), and Tyrosine Kinase Inhibitor (TKI) combination.

Timeline

Start
2020-09-11
Primary completion
2024-01-18
Completion
2024-01-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Axitinib Small molecule
Subject Cabozantinib Small molecule
Subject Nivolumab Monoclonal antibody

Indications