drugset / Trial / NCT04555694

Comparing Treatment of Dry Eye With Intracanalicular Dexamethasone, Restasis, and/or Lotemax

NCT04555694

Phase 4 Completed 30 enrolled Thomas Chester, OD
RandomizedParallel-groupOpen-labelTreatment

Summary

This 6 month study seeks to compare the use of Intracanalicular Dexamethasone in conjunction with Restasis (cyclosporine ophthalmic emulsion) for the treatment of signs and symptoms of dry eye disease as compared to Restasis with Lotemax (loteprednol etabonate ophthalmic suspension 0.5%) and Restasis monotherapy.

Timeline

Start
2020-10-01
Primary completion
2022-02-16
Completion
2022-02-16

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cyclosporine Peptide Other
Comparator Dexamethasone Small molecule 0.4 mg Other
Comparator Loteprednol Etabonate Other / unclassified 0.5 % Other

Indications