drugset / Trial / NCT04562025
Clinical Research of UC-MSCs in the Treatment of Diabetic Nephropathy
Unknown
38 enrolled
Renmin Hospital of Wuhan University
Wuhan Hamilton Bio-technology Co., Ltd · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Diabetic nephropathy (DN) is one of the most serious complications of diabetes and the leading cause of end-stage chronic kidney disease. DN is a refractory disease with low awareness, high incidence, and high disability. The incidence of DN can reach 30 to 40% after 20 years of diabetes, of which 5\~10% of patients will progress to end-stage renal disease, and epidemiological surveys predict that by 2030, DN will become the seventh leading cause of death in the world. Currently, there are no effective drugs for treating DN. This clinical trial is to inspect the safety and efficiency of human umbilical cord mesenchymal stem cells (UC-MSCs) therapy for patients with DN.
Timeline
- Start
- 2020-09-25
- Primary completion
- 2021-09-25
- Completion
- 2021-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | mesenchymal stem cells | Cell therapy | 1e+06 cells/kg | Intravenous |