drugset / Trial / NCT04568200

Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Resectable Esophageal Squamous Cell Carcinoma

NCT04568200 ↗

Phase 2 Completed 60 enrolled Peking Union Medical College Hospital
RandomizedParallel-groupSingle-blindTreatment

Summary

This is a study to evaluate the efficacy and safety of preoperative treatment with durvalumab combined with neoajuvant therapy (carboplatin, paclitaxel with/without radiation) in locally advanced resectable oesophageal squamous carcinoma.

Timeline

Start
2020-06-19
Primary completion
2023-12-01
Completion
2024-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Durvalumab Monoclonal antibody 1500 mg Intravenous
Background Carboplatin Small molecule — Intravenous
Background Paclitaxel Small molecule 75 mg/m2 Intravenous