drugset / Trial / NCT04589429
Adding Nalbuphine for Control of Intrathecal Morphine Pruritus
RandomizedParallel-groupQuadruple-blindPrevention
Summary
Intrathecal morphine causes intense itching which is very bothersome. Nalbuphine antagonizes this effect when given intravenously. This trial is to find out if nalbuphine added to intrathecal morphine has an effect on morphine related pruritus while still maintaining adequate analgesia.
Timeline
- Start
- 2020-10-15
- Primary completion
- 2021-03
- Completion
- 2021-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Nalbuphine | Small molecule | 2 mg | Intrathecal |
| Comparator | Morphine | Other / unclassified | 0.3 mg | Intrathecal |
Indications
No indication recorded.