drugset / Trial / NCT04600115
New MRI Methods Applied to Heart Failure With Preserved Ejection Fraction (HFpEF)
Phase 0
Recruiting
100 enrolled
University of Utah
National Heart, Lung, and Blood Institute (NHLBI) · collab
NaSingle-groupOpen-labelHealth-services research
Summary
This study's main specific aims are; 1. To develop robust acquisition and reconstruction methods specifically for the study of microvascular cardiac remodeling with MRI which will include very innovative quantitative perfusion methods, as well as fibrosis quantification, longitudinal strain, and phase contrast imaging for flow. 2. Test the new methods for identifying the clinical task of characterizing HFpEF.
Timeline
- Start
- 2017-03-03
- Primary completion
- 2027-03-03
- Completion
- 2027-03-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Adenosine | Small molecule | 0.14 mg/kg | Intravenous |
| Background | O-15 labeled radioactive water | Diagnostic / imaging agent | 1850 mbq | Intravenous |
| Background | Regadenoson | Diagnostic / imaging agent | 0.4 mg | Intravenous |