Dexmedetomidine Infusion Effect on Hemodynamic Variables During Craniotomy

Summary

There is no clear consensus among neuroanesthesiologists regarding which anesthetic regimen is optimal for craniotomy. Propofol and short-acting opioids (such as remifentanil, fentanyl, or sufentanil) are commonly used. However, use of opioids is associated with increased risk of respiratory depression and postoperative nausea and vomiting. Dexmedetomidine is a highly selective α2-adrenoreceptor agonist that has been considered as a useful and safe adjunct to anesthesia for various surgical procedures

Timeline

Start

2020-11-21

Primary completion

2021-01-20

Completion

2021-01-26

Drugs

Indications