drugset / Trial / NCT04621526
Monitored Anesthesia Care: Dexmedetomidine-Ketamine Versus Dexmedetomidine- Propofol For Chronic Subdural Hematoma
RandomizedParallel-groupDouble-blindTreatment
Summary
Inadequate sedation and analgesia indicated by intraoperative movements are markers of inadequate MAC during burr-hole surgery for chronic subdural hematoma evacuation especially when general anesthesia poses high risk for the patients. Dexmedetomidine, ketamine, propofol intravenous infusion and other agents was used to provide monitored anesthesia care with variable success if used as solitary agents as each drug has its limited use.
Timeline
- Start
- 2020-11-10
- Primary completion
- 2023-08-30
- Completion
- 2023-08-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ketamine | Small molecule | 0.5 mg/kg | Intravenous |
| Comparator | Propofol | Small molecule | 0.5 mg/kg | Intravenous |
| Comparator | Dexmedetomidine | Other / unclassified | 0.5 ug/kg | Intravenous |
Indications
No indication recorded.