drugset / Trial / NCT04621981

Sodium Bicarbonate Ringer's Solution Versus Normal Saline for Early Fluid Resuscitation in Patients With Sepsis

NCT04621981

RandomizedParallel-groupOpen-labelTreatment

Summary

At present, people still have different opinions on choosing which kind of crystalloid solution for patients with sepsis, and there is no unified standard yet. It is necessary to conduct systematic studies on comparison of different fluid resuscitation methods on the efficacy and safety of crystalloid solution for patients with sepsis. Therefore, this study focuses on the efficacy and safety of sodium bicarbonate Ringer's solution compared with normal saline.

Timeline

Start
2021-03-11
Primary completion
2022-09-30
Completion
2022-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Sodium Bicarbonate Ringer's Solution Unknown 500 ml Intravenous
Subject Sodium Bicarbonate Ringer's Solution Unknown 1000 ml Intravenous
Comparator sodium chloride Unknown 500 ml Intravenous
Comparator sodium chloride Unknown 1000 ml Intravenous