drugset / Trial / NCT04621981
Sodium Bicarbonate Ringer's Solution Versus Normal Saline for Early Fluid Resuscitation in Patients With Sepsis
RandomizedParallel-groupOpen-labelTreatment
Summary
At present, people still have different opinions on choosing which kind of crystalloid solution for patients with sepsis, and there is no unified standard yet. It is necessary to conduct systematic studies on comparison of different fluid resuscitation methods on the efficacy and safety of crystalloid solution for patients with sepsis. Therefore, this study focuses on the efficacy and safety of sodium bicarbonate Ringer's solution compared with normal saline.
Timeline
- Start
- 2021-03-11
- Primary completion
- 2022-09-30
- Completion
- 2022-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sodium Bicarbonate Ringer's Solution | Unknown | 500 ml | Intravenous |
| Subject | Sodium Bicarbonate Ringer's Solution | Unknown | 1000 ml | Intravenous |
| Comparator | sodium chloride | Unknown | 500 ml | Intravenous |
| Comparator | sodium chloride | Unknown | 1000 ml | Intravenous |