drugset / Trial / NCT04627740

Anti-ALPP CAR-T Cells Immunotherapy for Advanced Solid Tumors

NCT04627740

NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to evaluate the safety and efficacy of anti-ALPP chimeric antigen receptor (CAR)-modified T (CAR-T) cells in treating patients with ALPP-positive Advanced Solid Tumors.

Timeline

Start
2020-12-01
Primary completion
2025-02-28
Completion
2025-08-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Anti ALPP CAR-T cells Cell therapy
Background Cyclophosphamide Other / unclassified 20 mg/kg
Background Fludarabine Small molecule 35 mg/m2

Indications