drugset / Trial / NCT04628559
Comparison of the Perioperative Effects of Dexmedetomidine and Ketamine Sedation in Septorhinoplasty Operations
RandomizedParallel-groupTriple-blindTreatment
Summary
This randomized double-blind study aimed to compare the effects of dexmedetomidine and ketamine on hemodynamic parameters, recovery criteria, and opioid consumption and advers effects in septorhinoplasty operations. Totally 63 patients were included. The groups were compared in terms of hemodynamic values, recovery times, postoperative agitation, sedation, activity, modified Aldrete and pain scores, side-effects and additional analgesia requirements at postoperative 24h.
Timeline
- Start
- 2009-07-01
- Primary completion
- 2009-12-30
- Completion
- 2009-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | 0.4 ug/kg | — |
| Comparator | Ketamine | Small molecule | 10 ug/kg | Intravenous |