drugset / Trial / NCT04628559

Comparison of the Perioperative Effects of Dexmedetomidine and Ketamine Sedation in Septorhinoplasty Operations

NCT04628559 ↗

Completed 63 enrolled Karadeniz Technical University
RandomizedParallel-groupTriple-blindTreatment

Summary

This randomized double-blind study aimed to compare the effects of dexmedetomidine and ketamine on hemodynamic parameters, recovery criteria, and opioid consumption and advers effects in septorhinoplasty operations. Totally 63 patients were included. The groups were compared in terms of hemodynamic values, recovery times, postoperative agitation, sedation, activity, modified Aldrete and pain scores, side-effects and additional analgesia requirements at postoperative 24h.

Timeline

Start
2009-07-01
Primary completion
2009-12-30
Completion
2009-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexmedetomidine Other / unclassified 0.4 ug/kg —
Comparator Ketamine Small molecule 10 ug/kg Intravenous

Indications